Booth and Kim (2012) micro-BBB device
Here is the paper I reviewed at the NRG meeting on 06/19.
I’ve also included my presentation:
This week I’m working on designing the basal and apical chambers, considering the necessary shear stresses.
Here is the paper I reviewed at the NRG meeting on 06/19.
I’ve also included my presentation:
This week I’m working on designing the basal and apical chambers, considering the necessary shear stresses.
Last week, we reported that it was possible to anneal membranes after they had been etched. Below is a summary of results from membranes that were annealed over a range of temps and under different conditions. w600 (20 nm oxide) w510X (40 nm oxide) amorph. anneal 700 C no defects no defects amorph. anneal 750…
Using fresh tips, I re-ran the scans of amorphous Si films deposited at different biases. Recall that our theory states that interface roughness between the Si/SiO2 is an important determinant for ultimate pore morphology. A rough interface will suppress nucleation, which is why we observe low porosity with zero bias. The 05 W condition decreases…
Note: a postscript regarding an assay to determine the activity of our MMP-2/MMP-9 inhibitor was added to this post on June 14, 2021. Introduction The blood-brain barrier (BBB) plays an important role in maintaining brain chemistry by restricting the permeability of small molecules and cells. Inflammatory diseases may disrupt the BBB and promote the development…
Because I’ve been having such a difficult time measuring consistent zetapotentials (a big and heartbreakingly inconclusive post on those efforts is forthcoming) I decided to use one of my silver-coated SNMs as an EO pump and see if changing the voltage applied to the membrane changed the rate of EO. And I’m very happy to…
While performing an experiment to study HUVEC growth rates on various substrates, I observed an interesting phenomena on the oxide membranes. I was using 120nm, nonporous, 600C annealed SiO2 membranes in this trial. The cells were observed at least once per day over a course of 173 hours from seeding. The growth rates and quantitative…
This is just an update for the experiments Tejas and I have been working on for the past two weeks: First, we tried incorporating 20 μl of Geltrex (10 mg/ml, diluted with DMEM from stock concentration: i.e. 15.6 mg/ml) in the back of a non-porous chip with 0.02 μm blue fluorescent nano-spheres (1:10 dilution from stock concentration)….