m-µSiM platform: TEER and Permeability for Open-Well iPSC-ECs and viability test for future flow module
Introduction Tissue barriers regulate the absorption of nutrients, maintain homeostasis, and prevent toxins from entering. As previously introduced, trans-epithelial/endothelial electrical resistance (TEER) measurements offer a non-destructive and real-time method to quantitatively evaluate the integrity of tissue barriers. During the process, a small AC current (10 µA, 12.5 Hz) is applied across the barrier while the…