Nanopores May Eliminate Current Evaluation Processes Used for Detecting Epigenetics-Related Diseases

The x-values are based on TEM images of the last populations of gold nanoparticles (I think. I can’t remember immediately when the fridge died on us). It’s probably worth re-doing that with the new gold vials. There’s still some work to be done. In the 50 nm NPN, 5 nm gold was only done once,…

A few weeks ago, we made wafers with three different silicon thicknesses: 15 nm, 30 nm, and 50 nm. The goal was to see how pore morphology changes with increasing thickness. The films were deposited at 450 C with a 25 W substrate bias. The annealing temperature was 800 C in the susceptor. Note that…

We manufactured a wafer specifically for SERS experiments in the hope of recapturing larger pore distributions/pore densities that we observed in some of the prototype runs of NPN. Natively, it’s a little thicker, and a little less porous than the 1085 material. By partially etching the membranes from the backside, we should be able to…

Introduction We are aiming to make device assembly easy and quick, particularly for distribution to non-engineering laboratories. We are collaborating with ALine to develop assembly via pressure-sensitive adhesion techniques. Assembly Process Modular Device Assembly Animation2 We made ten devices with porous membranes and ten with non-porous membranes to show no leakage. Current Issues and Potential…

Here is a better, more thoughtful, attempt at pore processing of a single image of the backside of a 75-nm thick membrane (four slot). One thing you will note that could be different from the analysis of the frontside of the membranes: The small openings that appear quite sharply defined here could be missing from the frontside…