Not exactly related..but a nice read

We still have plenty of things to do, but after five weeks working at the UR, we have come a long way: – Chip production for instructional use:  done – Design and production of SU8 mold: done – Protocols for (@Fisher) manufacture of micro and milli (silhouette) fluidic devices: done – Construction and testing of chips…

Josh has just started teaching us how to play with these; some early findings: – So far, standard centrifugation results mostly on the caking of lipids that clogs the membranes. – Use of the pressure cell has shown some promise, we have passed 120nm lipid-nps through 400nm pores @10PSI.  The result?  70nm particles… – Reverse…

Summary My analysis of npMgF2 has relied heavily on both tomogram and segmentation processes. The tomogram generation has thus far been sufficient, giving enough detail to our eye to identify different structures, but turning the tomograms into 3d models has been a lot more labor intensive. Using a neural network classifier (Weka, out of a…

In my previous post talking about the contact angle measurement of 3-mer coated PEG, there was a lack of adequate controls, and also an unanswered issue of contamination of samples during storage. I would now like to refine the study in more -controlled fashion, and without reusing the old chips. In addition, I am also…

Over the past week Andrea and I designed a new co-culture support structure for use with SiMPore’s 5.5 mm square membranes. The devices are built for use in standard 24-well plates and should prove useful to anyone wanting to do basic co-culture with these membranes going forward. The device is constructed of PDMS rings as…

Here is a slightly enhanced version of Mike’s latest hydraulic permeability data for commercial devices with PES membranes. The data at 22 and/or 34 PSI are a bit strange. Still the long-term trend seems downward. Similar data for PNC-Si membranes should show no pressure dependence. We need to get a version of this figure that…