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Nanomembrane Research Group
  • Wafer #240919-19 – 3 μm Dual Scale – Low Porosity
    Wafer QC Pages

    Wafer #240919-19 – 3 μm Dual Scale – Low Porosity

    ByAhmet Gurcan June 5, 2025June 5, 2025

    Manufacturer’s Data Delivery Date: 2/5/2025 (picked up and logged by Ahmet Gurcan) Membrane Type:  NPN 3 micron Dual Scale SKU: DSSN100-1L-3.0-A1 (0.625% Porosity – Not real porosity) Lot Number: 240919-19 Quantity Received: 70 Manufacturer Test Report: Average Porosity (nanoporosity): Average Diameter (microporous): Average Diameter (nanoporous): Average Flux @ 1 PSI: Average Flex @ 2 PSI:…

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  • Wafer #240919-02 – 3 μm Dual Scale – Low Porosity
    Wafer QC Pages

    Wafer #240919-02 – 3 μm Dual Scale – Low Porosity

    ByAhmet Gurcan June 5, 2025June 5, 2025

    Manufacturer’s Data Delivery Date: 2/5/2024 (picked up and logged by Ahmet Gurcan) Membrane Type:  NPN 3 micron Dual Scale SKU: DSSN100-1L-3.0-A1 (0.625% Porosity – Not real porosity) Lot Number: 240919-02 Quantity Received: 200 Manufacturer Test Report: Average Porosity (nanoporosity): 27.2% Average Diameter (microporous): 2.84 μm Average Diameter (nanoporous): 49.2 nm Average Flux @ 1 PSI:…

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  • Wafer #240919-03 – 3 μm Dual Scale – Low Porosity
    Wafer QC Pages

    Wafer #240919-03 – 3 μm Dual Scale – Low Porosity

    ByAhmet Gurcan June 5, 2025June 5, 2025

    Manufacturer’s Data Delivery Date: 2/5/2024 (picked up and logged by Ahmet Gurcan) Membrane Type:  NPN 3 micron Dual Scale SKU: DSSN100-1L-3.0-A1 (0.625% Porosity – Not real porosity) Lot Number: 240919-03 Quantity Received: 230 Manufacturer Test Report: Average Porosity (nanoporosity): 27.2% Average Diameter (microporous): 2.84 μm Average Diameter (nanoporous): 49.1 nm Average Flux @ 1 PSI:…

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  • Wafer #240919-01 – 3 μm Dual Scale – Low Porosity
    Wafer QC Pages

    Wafer #240919-01 – 3 μm Dual Scale – Low Porosity

    ByAhmet Gurcan June 5, 2025June 5, 2025

    Manufacturer’s Data Delivery Date: 2/5/2025 (picked up and logged by Ahmet Gurcan) Membrane Type:  NPN 3 micron Dual Scale SKU: DSSN100-1L-3.0-A1 (0.625% Porosity – Not real porosity) Lot Number: 240919-01 Quantity Received: 180 Manufacturer Test Report: Average Porosity (nanoporosity): 28% Average Diameter (microporous): 2.88 μm Average Diameter (nanoporous): 49.4 nm Average Flux @ 1 PSI:…

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  • Wafer #240919-06 – 3 μm Dual Scale – Low Porosity
    Wafer QC Pages

    Wafer #240919-06 – 3 μm Dual Scale – Low Porosity

    ByAhmet Gurcan June 5, 2025June 5, 2025

    Manufacturer’s Data Delivery Date: 2/5/2025 (picked up and logged by Ahmet Gurcan) Membrane Type:  NPN 3 micron Dual Scale SKU: DSSN100-1L-3.0-A1 (0.625% Porosity – Not real porosity) Lot Number: 240919-06 Quantity Received: 210 Manufacturer Test Report: Average Porosity (nanoporosity): 29.1% Average Diameter (microporous): 2.83 μm Average Diameter (nanoporous): 48.7 nm Average Flux @ 1 PSI:…

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  • Wafer #240919-05 – 3 μm Dual Scale – Low Porosity
    Wafer QC Pages

    Wafer #240919-05 – 3 μm Dual Scale – Low Porosity

    ByAhmet Gurcan June 5, 2025June 5, 2025

    Manufacturer’s Data Delivery Date: 2/5/2025 (picked up and logged by Ahmet Gurcan) Membrane Type:  NPN 3 micron Dual Scale SKU: DSSN100-1L-3.0-A1 (0.625% Porosity – Not real porosity) Lot Number: 240919-05 Quantity Received: 230 Manufacturer Test Report: Average Porosity (nanoporosity): 31% Average Diameter (microporous): 2.84 μm Average Diameter (nanoporous): 48.8 nm Average Flux @ 1 PSI:…

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  • TRACE

    2025 Rochester MPS Day

    ByYonjong Choi April 25, 2025

    The 2025 Rochester MPS Day Summary provides an overview of the event, highlighting registration details, participant feedback, and suggestions for future improvements. The event had a total of 130 registrations, with 88 in-person and 26 virtual attendees. Participants represented various organizations, including the University of Rochester, RIT, Duke, NIH/NCATS, and several industry partners. Feedback indicated that…

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  • TRACE

    CRS Generated from Bispecific T Cell Engagers (BiTEs)

    ByJim April 25, 2025

    CRE_Bispecific_Antibody_CRS_and_ICANS_Neurotoxicity_Guidance_Feb2024 51899285fnl_Immunotoxic Potential of PharmaceuticalsWe are considering Bispecific T cell engagers (BiTEs) [1] as an alternative to a CAR T driven cytokine release as an immunotherapy focused DDT. BiTEs are monoclonal antibodies engineered to have one arm that recognizes a T Cell surface antigen and another that recognizes a tumor antigen. There are number of…

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  • IMR90 EECM-BMEC-Like Cells Lack P-gp Efflux Activity
    TRACE

    IMR90 EECM-BMEC-Like Cells Lack P-gp Efflux Activity

    ByLouis Widom April 25, 2025April 28, 2025

    Introduction During the January TraCe-bMPS progress meeting, Jon Flax presented some interesting findings in the iPSC-derived extended endothelial culture method brain microvascular endothelial cell-like cells (EECM-BMECs, hereafter referred to as BMECs) [1]. While these BMECs tended to have high expression of most transmembrane transport proteins, they had relatively low expression of p-glycoprotein (ABCB1/MDR1) (Figure 1)….

    Read More IMR90 EECM-BMEC-Like Cells Lack P-gp Efflux ActivityContinue

  • Establishing Flow Bumper Supported Basal Flow in Incubator & Best Practices
    TRACE

    Establishing Flow Bumper Supported Basal Flow in Incubator & Best Practices

    ByGram Hepner April 16, 2025April 17, 2025

    Introduction The modular µSiM device allows for active flow and continuous monitoring, but the acrylic-needle interface may experience incomplete sealing over longitudinal studies, so the need for an adaptable and intuitive approach for leak-free bottom-channel flow arose. Jordan Jones, Ahmet Gurcan, and Kevin Ling adapted the flow inserts to develop Flow Bumpers, a PDMS-adhesive component…

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    • Home
    • Publications
    • Membranes
      • Common Chip Formats
      • Common Membranes
      • Microslit Membranes
    • Devices
      • µSiM
        • Geometry
        • µSiM CAD Files
        • Assembly
          • Protocols.io (µSiM Assembly)
          • Instructions
          • Common Issues and Troubleshooting Tips
        • Cell Culture Protocols
          • Top Well: hCMEC/D3
          • Top Well: HUVEC
          • Bottom Channel Culturing
          • Immunocytochemistry Protocol
          • Impact of Chip Orientation on Fluorescence Imaging
          • Permeability: In Situ Method
          • Permeability: Sampling Method
          • Cell Culture Common Issues and Troubleshooting Tips
      • SepCon®
        • Sepcon Assembly
        • Sepcon Video Protocol: Assembly
        • SepCon Gasket Silhouette File
        • SepCon Video Protocol: Wetting the membrane
        • SepCon Video Protocol: Disassembly
      • µSiM-DX
        • µSIM Video Protocol: Capture of Nanoparticles
    • Impact
      • TraCe-bMPS
      • HCIC
      • LOMP
      • SiMPore