Hey all,
Here’s my thesis: ksmith thesis
I filmed the public portion of my defense and posted the video to youtube.
I’m not leaving till the end of the week, and I’ll be back for a week in mid-May as well as being generally around Rochester this summer (this isn’t goodbye!) but my permanent email address will be karljpsmith@gmail.com.
Keep the dream alive!
Introduction In our labs previously work, difficulties in growing endothelial cells (ECs) under shear flow lead to the exploration of novel membrane technologies that permit firm EC attachment, without compromising membrane permeability or leukocyte transmigration studies. We ultimately landed on the development of effectively ‘dual-scale’ membranes that contained 3 μm pores dispersed amongst an NPN…
What is SiR-DNA? It is a far-red DNA stain, known as SiR-Hoechst, and can be used for live-cell imaging. Most current DNA dyes are toxic or affect the cell’s motion or proliferation. https://www.nature.com/articles/ncomms9497 It does not affect the migration of human dermal fibroblast cells (hdFb). The motility parameters (speed and displacement) for a 24 hour…
Membranes Promote Endothelial Differentiation of Adipose-Derived Stem Cells and Perivascular Interactions Submitted to Journal of Cellular and Molecular Bioengineering (a BMES journal) ADSC-All-Figures FIGURE 1. Ultrathin microporous silicon dioxide (SiO2) membranes. (A) 300 nm thick SiO2 membranes were fabricated on silicon wafers and etched into 5.4 x 5.4 mm dies with 2 x 2…
Comsol modeling was done to find the ideal channel height and volumetric flow rate. What is clear from the simulation is that ever increasing flow rates in the model lead to increased clearance and decreasing channel heights give some benefit but not on the order previously expected. In addition, (Depner 2005) shows that increasing the flow…
Today while I was imaging a Al2O3 coated pnc-Si membrane on the high-res TEM, I noticed something curious as I placed the beam on a single pore for a few minutes. I was initially interested in the structure of the aluminum oxide coating, but found that something started to deposit on the pore walls as…
Nanobattery Paper Nanobattery Supplement I have long desired to make energy storage devices with our nanomembranes (supercapacitor post), mainly because they would be really great separators, having both excellent charge conduction and physical barrier resistance due to the porosity and material properties of silicon. Other groups have begun to take advantage of the increased…