R6G diffusion observed through the plastic substrate

Introduction Over the past two decades there has been little to no improvement in treatment for people who have end stage renal disease (ESRD). The two main methods of treatment for ESRD are kidney transplant or dialysis. However, due to the limitations involved with transplantation, the majority of patients receive dialysis. It has been speculated…

The new bottle of PVP (polyvinylpyrrolidone) sitting on the shelf was calling my name this morning. I apologize that this post is long, but its pretty exciting – I think we have half-solved the wettability problem. According to MSDS sheets, PVP is soluble in water and alcohols. Since drying water on the membrane is a…

ALine Capture Device In this post I will go over some of my recent work that is a continuation of Kilean’s research concerning extracellular vesicle (EV) capture and characterization. In the past, this was done using a tangential flow filtration (Figure 1) scheme and clamped devices featuring nanoporous membranes (Figure 2). These devices are straightforward…

The aim of this work was to electrospin aligned polymeric fibers on parylene stencils as means to characterize the critical necessary total area and necessary opening sizes to elicit endothelial cell response in the form of cell alignment among other characteristics typically found in human cells that are adjacent to highly aligned ECM. For this…

Power Point for my Senior Design   https://docs.google.com/file/d/0B1AH05-mf_tQLTdSMHRWX0NjNGc/edit?usp=sharing  

I have created a successfully sealed flow chamber with this current device (V2.4), with the caveat that I sealed off the top chamber and was unable to test leaking from the top to the bottom. Again, the dialysis chips from Dean’s work were used, as well as the same bulk microscope slide electrodes.   Improvements…