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Ultrathin Freestanding Nafion Membrane
ByJirachaiUtilizing a cation-exchange membrane like Nafion makes it possible to electrically induce the concentration difference across the membrane. The resulting osmosis of water augments the overall flowrate in addition to the electroosmosis. The thinner the membrane, the stronger the osmotic flow is induced electrically. This behavior can be predicted from the conventional transport model for…
Polarized TNF-α Update: rhIL-8 and PMN Persistence
ByAlecIntroduction In a previous post I introduced the concept of endothelium apicobasal polarity and the potential to utilize this concept for future sepsis drug development: Endothelium Apicobasal Polarity Regulates the Innate Immune Response In Vitro [In Progress] In this post, I will expand on the ‘mock’ TNF-α experiments with recombinant IL-8 as well as add…
SiO2 evaporation at RIT
ByJimToday Barrett and I processed SiO2 deposition at RIT. This process was actually delayed due to the cleanroom scrubber failure last week. We deposited 30nm SiO2 on both sides of three wafers, #335, 341, and 345. Earlier in March, I tried 20nm and 40nm SiO2. It was found that 40nm SiO2 is so thick that…
Sepsis and Sepsis-Associated Neutrophil Dysfunction – BMES 2019
ByAlecIntroduction Sepsis related projects had a decent presence at this years Biomedical Engineering Society (2019). I will detail a few of the talks I found most relevant to our group and research. Nanomedicine for Acute Criticial Illness by Dr. Jacob Brenner (U Penn Medical) Dr. Brenner is a practicing physician working on ICAM-1, PECAM-1, and…
Electron Beam Evaporation, RIT vs UR
The CHA e-beam evaporator in RIT had been used traditionally for the deposition of metal on the pnc-Si membranes. The most important factor for metal deposition on the membranes is that the nanoholes must not be blocked. So the metal deposited needs to be smooth and continuous. Ag or Au does not adhere onto Si…
SEM of geltrex coating on SiN membrane
ByHenryHi all, A while back we have shown that geltrex coating enhances the attachment of HUVEC on SiN membrane . Jim believes that geltrex may be extended an “all-purpose” coating to promote the adhesion of different cell types to the SiN membrane, but worries that the geltrex coating maybe too thick (e.g. tens of microns), which…