TraCe Progress: September 2025
- Administrative:
- Molly Van Wyk is no longer TraCe-bMPS admin. Assumed Bonnie’s job as Sr. Admin in BME. Will continue to help until position is replaced.
- Quality Systems meetings are moving to Wednesdays only: 9:30 -10:00 AM
- Progress meetings will be on Tuesdays 9:00 – 10:00 AM starting in Spring. One more 4 PM meeting planned this year: October 24.
- External Advisory Board Visit on October 17 – Local labs should be prepared for visits by B&L scientist
- Publications:
- Chen K, Linares IM, Trempel MA, Feidler AM, De Silva D, Farajollahi S, Jones J, Kuebel J, Kasap P, Engelhardt B, Flax J, Abhyankar VV, Waugh RE, Gelbard HA, Terrando N, McGrath JL. (2025) Shear Conditioning Promotes Microvascular Endothelial Barrier Resilience in a Human BBB-on-a-Chip Model of Systemic Inflammation Leading to Astrogliosis. Adv Sci e08271. https://doi.org/10.1002/advs.202508271
- Cognetti, J.S.; Miller, B.L. Real-Time, Continuous Monitoring of Tissue Chips as an Emerging Opportunity for Biosensing. Sensors 2025, 25, 5153. https://doi.org/10.3390/s25165153
- Presentations:
- Adamo and McGrath, CTSI Grand Rounds, September 11, 2025
- Pharma update
- Pfizer meeting (CRS – ICANS). Good idea. Validation showing ability to capture donor diversity desired before this would be used by Pfizer.
- Apoglyx project launch (Dan will post and review in November).
- TraCe Services soft launch … moving to shop credit model and tiered membership access to materials, protocols, etc.
- Quality Systems
- VABF: RIT external reproducibility study is done. Duke in progress. Will write up a post when done.
- NUTEM: neutorophil transmigration launched.
- LOIs
- JDM is back to C-Path for final review before FDA submission (will post with submission)
- CRS-ICANS still being revised based on 1st C-Path review
