Silicon Ideal to Culture Patient-On-a-Chip | Insight & Intelligence™ | GEN

This is an update of the research on the on-chip EO pump. Due to a mistake in determining the direction of particle flow, it now looks like the particles in this post were moving by electrophoresis rather than electroosmosis.  The particles were negatively charged (-40 mV zeta potential) because of a COOH group on the…

In this post I’m trying to give a better comparison among filtrations using chips from wafer 1085 using 20 and 100 nm fluorospheres, IgG, and 5 and 20 nm Au NPs.  In each slide I try to indicate the flow direction with respect to the membrane.  Unless I’ve written “Pressure” near the direction the separations…

Summary Since our last attempt, Greg and I have been attempting to refine our tenting experiments with the goal of demonstrating that we’re able to hydrate the volume underneath a nanoporous tent. This latest experiment is very similar to our previous experiment in theory, but we made some key changes which are discussed herein. Most…

One of the hidden secrets of endothelial angiogenesis assays on Matrigel is that non-endothelial cell types also form 2D capillary-like structures (tubes) on those gels.  Motivated by this observation, I wanted to look at fibroblast behavior on pnc-Si transwells, specifically with respect to whether or not they formed vacuoles.  Just to clarify – although Anant…

In the last few weeks, the production team has focused on making strong, stable, porous material with the AJA sputter system.  In the process, we’ve RTPed a wafers over a wide range of temperatures under different deposition conditions.  We found that it’s possible to make membranes that range from non-porous to highly porous along with…