The role of tRNAs on Cell Phenotypes

For the past few weeks, Henry and I have been working with human dermal fibroblast cells and 3T3 mice fibroblast cells. We have been working to quantify wound recovery in hopes to be able to incorporate exosomes from different cell lines to see the effects on wound healing. The NIH 3T3 cells are small cells…

This is a followup to my previous post, found here. Some of the data in that post is now outdated and will be replaced with newer data here. I’ve added to the comparison the diffusion of cytochrome C and urea through a polyethersulfone “high-flux” membrane. This material is commercially available just like the cellulose triacetate….

Introduction & Motivation A subset of cancer cells has mutations that generate proteins recognized by the immune system as foreign, triggering the immune-mediated clearance of those cells. To avoid this fate, cancer cells can evolve mechanisms to suppress this antitumor response via the regulation of immune checkpoint pathways. Immune checkpoints describe mechanisms that are in…

von_der_Mark_2012 Here is some data on cell growth on different porosity TiO2 nanotubes.  The above paper is an earlier publication regarding the work presented in Poster form at PSST 2014.  Below are photos taken from the 4 quadrants of the poster.      

Last week I tried to diffuse Cytochrome C through our membranes onto PVDF and PES membranes to see if we can detect protein adsorption on the other membranes. The trial illustrated that cytochrome c will diffuse through our membranes and stick to the PVDF and PES membranes. I ran the experiment again, but I used…