Contrast agents are used to increase received signal in imaging systems. In the case of ultrasound, such agents are small micron sized gas bubbles. Ultrasound measures the change in acoustic impedance (product of density and speed of sound), but since the speed of sound in tissue is relatively constant, medical ultrasound effectively measures changes in…
Blender is a free, open-source software package for modeling 3d objects. While Sketchup is much easier to learn, it has a number of limitations that make it more difficult to do more detailed modeling. Blender has a plethora of features, including cloth, particle, and water simulation, that make it very useful. You can also design and…
Presentation split into 3 parts: Raman-silent nanomembranes for cell-culture: raman-silent-cell-culture-project Nanomembrane Tenting: dna-ssnp-project SERS sensing membrane: sers-sensing-project
Hello All, My name is Dan Steiner and I am a rotation student that has been working with Dean on designing a modular benchtop apparatus to study in vivo blood dialysis. The purpose of this project is to create a dialysis system with the ability to scale up previous ultrathin silicon membrane dialysis experiments to…
Power and battery life for wearable hemodialysis. The pump(s) will consume the most energy of all the components of the system. Other power consumers could include, control circuits, wireless communication, display and warning lights, depending on design. A continuous display could consume a great deal of power if not handled correctly. LEDs and LCD indicators…
The purpose of this post is to start a general discussion around the idea of using ultrathin silicon-based membranes and graphene oxide to improve Extracorporeal Liver Support, also called Artificial Liver Support (ALS) for patients with acute liver failure (ALF). What is Extracorporeal Liver Support? This is essentially the equivalent of renal dialysis for the liver….
Our collaborator Fernando has made a really nifty way to make microfluidics work with lamination pouches. These flat pouches can be sealed together using a heat activated glue, which can be done consistently using a 15 for a 100-pack of 8.5″x12″ pouches + $40 laminator Put multiple materials and multiple chips in the same microfluidic package….
I wish I had read Tucker’s lat post before trying this, but since I just got the steam jig from the machine shop I wanted to try it out. My mistake in the two transfers I attempted was that I applied the steam evenly as opposed to the suggested 45 degree angle, but the results…
The company Protochips is making interesting microfluidic chips and systems for electron microscopy. See this page and this movie. Note their use of integrated spacers as thin as 150 nm to create a flow channel between back-to-back membrane chips. This not only relates to our work with Vincent in Ottawa, perhaps it gives us new…
Hi all, This post showcase a simple (low-tech) alignment tool for assembling the different components of a microfluidic chamber. Essentially, the alignment pieces are made from two index papers cut using the Silhouette Cameo. The two cut index papers are bonded together using double-sided tapes. The square holes are where the membrane chips are to…