These are low burst results but samples have lots of pinholes on them many of which are on the edges.
I also checked porosity of the wafers 338 and 340. They indeed have porosities close to 7%.
Wafer 340 (0,5) 0.0656 porosity
Introduction The invasion of Staphlyococcus aureus into the cracks of cortical bone leads to osteomyelitis, a devastating disease often resolved by amputation [1]. The μSiM platform has been used to study the genetic mechanisms of S. aureus invasion. The membrane pores mimic the network of cracks in bone, referred to as the osteocyte lacuno-canalicular network…
During the last weeks of my rotation, Tejas and I attempted to study neutrophil migration in the following setup, using fMLP as a chemoattractant: In order to do this, we permanently bonded a 1 mm PDMS gasket to the bottom and top sides of a 3 micron microporous SEPCON and filled the back side (which is…
This is an update of my progress with the diffusion model. Sieving coefficients for standard setup (Renkin only) In this image there’s a strong sigmoidal curve for the 24 hour diffusion. However, the cutoff (~34nm) is higher than cutoffs found in experiments. The lower time curves have unexpected shapes. This may be due to…
Introduction The blood-brain barrier (BBB) plays an important role in maintaining brain chemistry by restricting the permeability of small molecules and cells. Inflammatory diseases may disrupt the BBB and promote the development of neurological disorders [1]. One potential mechanism of BBB disruption is the degradation of the extracellular matrix proteins that make up the endothelial…
A few weeks ago, professor Mike Aziz in Harvard University helped to annealed two samples and in-situ imaged the early stage of pore formation using their Jeol2010-hot-stage-TEM. The oxide seemed intact during the process. The sample was unannealed 20(bottom)/15(a-si)/10(top) three stack with removing the substrate. The first sample was heating to 693C. They took one…