Journal Club for June 6. Voting is Now Open.
Voting is open until NRG tomorrow. We’ll critically discuss the winner and summarize the 2nd place paper.
[yop_poll id=”3″]
Voting is open until NRG tomorrow. We’ll critically discuss the winner and summarize the 2nd place paper.
[yop_poll id=”3″]
The following plot is an attempt to summarize recent work measuring rate of flow through a membrane as a function of concentration. We investigated 100 nm NPs, (totally blocked), 20 nm NPs (partially blocked) and IgG (mostly passed). In all cases, the buffer used was 1xPBS and 0.1% Tween 20. This plot mostly shows the total…
I have created a successfully sealed flow chamber with this current device (V2.4), with the caveat that I sealed off the top chamber and was unable to test leaking from the top to the bottom. Again, the dialysis chips from Dean’s work were used, as well as the same bulk microscope slide electrodes. Improvements…
The paper that came out from Shigeru’s laboratory earlier this year in Analyitical Chemistry (Ishimatsu et al. 2010 downloadable here) demonstrated that the permeability of pnc-Si membranes to small monovalent ions in 0.1 M salt is predictable from membrane geometry alone. The paper also shows that multivalent and/or large ions do not follow theory as…
Hi all, This post showcase a simple (low-tech) alignment tool for assembling the different components of a microfluidic chamber. Essentially, the alignment pieces are made from two index papers cut using the Silhouette Cameo. The two cut index papers are bonded together using double-sided tapes. The square holes are where the membrane chips are to…
Initial studies into the mechanical properties of pnc-Si were carried out using the “bulge test”. With JP’s help, we’ve collected a large amount of pressure-displacement measurements. This technique has been used to investigate thin film membranes suspended over windows of different geometries e.g. Vlassak. In this study, we measure the deflection of a pressurized membrane…
The basics of this device are… Blood flows through a filter made of zeolite containing nanofibers. While the blood flows transversely through the mesh, creatinine can diffuse through the mesh where zeolites stand by to grab them via size selecting capture. Their experiments were done with 190 µM creatinine solution. MW of creatinine is 113.1179…