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New metal coated wafer#502
ByJimWafer#502 was coated with 10nm_Ti & 15nm_Au on Friday. I will pick out pinhole free membranes later today. I will also try to get TEM images at Karen’s lab (medical center). // The RIT clean room is closed this week.
microEO: bead pumping
Charles developed a new microEO chamber, and I did some quick particle tracking experiments. The fluid in front of the membrane was filled with 200nm fluorescent polymer beads, and the power supply was used to cause the fluid to flow within the chamber. Bead speed was measured with Henry’s particle tracking programs. Picture of microEO:…
Investigating the potential of astrocytes as a neuroinflammation markers by assessing their activation state
Introduction Astrocytes, which are the most abundant glial cells and key components of the BBB, are known to play crucial roles in initiating and responding to neuroinflammation.1 Astrocytes’ activation after injuries suggests that they could potentially serve as a marker of neuroinflammation. In this blog, I investigated the potential of astrocytes to serve as a…
Rotational and translational diffusion of DNA in a nanopore
Small DNA oligomers behave like stiff cylindrical rods. They have both rotational and translational diffusion, and this is of interest when considering how such a rod will diffuse through a nanopore. In this post I briefly consider the effects of rotational and translational diffusion of cylinders of different lengths. The rotational diffusion coefficient can be…
Excimer laser annealing of sputtered three-layer stack (1)
ByJoe QiHello everyone! I plan to write several posts in the next couple of weeks about the laser annealing of our sputtered three-layer stack. This laser annealing experiment is done at Center for Nanophase Materials Sciences (CNMS) at Oak Ridge National Laboratory (ORNL). It is a collaborational proposal we submitted at the end of last year…
Strutting the Runway: Modeling the Microfluidics and Reaction Kinetics of the μSiM-DX
The development of the μSiM-DX has been swift and focused, as discussed in these previous blog posts: https://trace-bmps.org/beadazzled-laying-the-foundation-of-the-%ce%bcsim-dx-fouling-based-sensor/ and https://trace-bmps.org/vindictive-virus-capture-testing-the-%ce%bcsim-dx-with-vaccinia-virus-towards-a-modular-virus-diagnostic/. To provide a greater understanding of the inner workings of the device, I have done a few calculations regarding some of its working properties related to microfluidics. The three I present here are about the relationship…