Permeability and burst pressures data for new wafers

I am trying to deposit metal on the membrane with minimal deposition inside the pores. The image below is an example of how the film quality and thickness change when the sample is positioned at different angles and distances from the source in the same deposition run. The schematic in the corner of each SEM…

Because our membranes are not mono-disperse, we often debate the relative contribution of large pores vs small pores in both diffusive and convective separations. Indeed it is possible that the way pores contribute to transport in these two modes is different and would give rise to different fractionations of the same sample with the same…

I wrote about my experiences tenting nanomembranes here. I delaminated NPN material across a bunch of substrates and found that the film would actually form a nanocavity if spread across a sufficiently small surface (I estimated it to be 1-2 microns over a 50 nm height difference). Simpore fabricated a number of small substrates with varying…

A quick recap:  Vaccinex has asked the lab to design a closed system device with the capability to co-culture on microporous membranes.  This device would be used to mimic the blood brain barrier, with endothelial cells cultured on the apical side and glial cells cultured on the basal side, and would allow for the testing…

In this post I will explain how I tried to use the 1D diffusion model to check the results we had in the Nature paper.  Unfortunately I didn’t get the same results in the simulation and I present some ideas for the discrepancy. In the Nature paper we made simple small volume diffusion chambers and…

Because of the failure of bonding the electrode to the top gasket in my last design, I have been trying to make improvements to my fabrication to make the electrode/gasket surface more planar. Things I have tried: 1. Pressure during curing. I placed a 500g weight on top of a microscope slide on top of…