Endothelial Vacuolization Induced By Highly-permeable Silicon Membranes

The coating was done last week at RIT (it was postponed from two weeks ago because of the failure of the e-beam crystal sensor). I deposited 10nm Ti and 15nm Au, without vacuum breaking. All the samples are from wafer #313. TEM images were taken yesterday with the help of Karen. (Her machine is really…

In the previous post, I discussed how we could evaluate the flux of molecules through the membrane and alluded that this method could be used similarly to our effective diffusion coefficient manner of evaluating membrane impact.  Here are results of the full comparison. Standard setup: 15nm membrane, 1 hour time point, 1mm fluid wells, 5%…

Introduction In previous posts by both Alec and Kayli, the urea clearance performance of our bench-top single-pass dialysis devices has been described. Results regarding devices containing untreated, PEG-treated, and nonporous membranes can be found in the “Current Dialysis Research [McGrath Lab, December 2017]”, https://trace-bmps.org/current-dialysis-research-mcgrath-lab-november-2017/ and “Updated Dialysis Research” posts. https://trace-bmps.org/updated-dialysis-research/ The nanomembranes present in these…

Just wanted to let everyone know that the fused silica capillary tubing and adapter needed to connect them to the pump tubing have been ordered and should be in hopefully by Friday (Monday at the latest).

Introduction These results are thanks to assistance from Sam Walker and his previous posts regarding urea clearance that helped lay the foundation of this experiment. “Single Slot Inverted-Chip and Double Slot: Single-Pass Dialysis Devices” (Walker 2018) https://trace-bmps.org/single-slot-inverted-chip-and-double-slot-single-pass-dialysis-devices/   More information on the Liftoff membranes can be found in the article cited below: “Lift-off of large-scale…