PEGS 2014
Protein and Antibody Engineering Summit – PEGS 2014
Our Poster: PEG2014_posterE
Below are a couple of presentations from the Protein Aggregation and Stability session that I will summarize.
Our Poster: PEG2014_posterE
Below are a couple of presentations from the Protein Aggregation and Stability session that I will summarize.
Hi all, This post showcase a simple (low-tech) alignment tool for assembling the different components of a microfluidic chamber. Essentially, the alignment pieces are made from two index papers cut using the Silhouette Cameo. The two cut index papers are bonded together using double-sided tapes. The square holes are where the membrane chips are to…
During our meeting with Vincent Tabard-Cossa from U Ottawa, we are going to explore the concept of using nano porous silicon nitride membranes in electronic detection schemes for identifying nucleic acid:small molecule complexes. The concept was demonstrated by Wanunu et al, Nano Letters, 2011, where they showed single nanopores were able to detect complexes of…
Hello All, My name is Dan Steiner and I am a rotation student that has been working with Dean on designing a modular benchtop apparatus to study in vivo blood dialysis. The purpose of this project is to create a dialysis system with the ability to scale up previous ultrathin silicon membrane dialysis experiments to…
The purpose of this post is to start a general discussion around the idea of using ultrathin silicon-based membranes and graphene oxide to improve Extracorporeal Liver Support, also called Artificial Liver Support (ALS) for patients with acute liver failure (ALF). What is Extracorporeal Liver Support? This is essentially the equivalent of renal dialysis for the liver….
For the upcoming tests I have planned for H2 purification, I need a fixture to hold the pnc-Si membranes (Sepcon format) that is compatible with operation up to 500 C. No polymers are going to work. I describe the approach I’m working on below. I heard that Karl is developing a holder similar to what…
Instantaneous Clearance: Kd CBi, and CBo are the concentration of solute in the blood at the input and output of the dialyser. CDi and CDo are the concentration of solute in the dialysate at the input and output. QBi, QBo, QDi, and QDo are the flow rates at the inputs and outputs. The volume of…