PEGS 2014
Protein and Antibody Engineering Summit – PEGS 2014
Our Poster: PEG2014_posterE
Below are a couple of presentations from the Protein Aggregation and Stability session that I will summarize.
Our Poster: PEG2014_posterE
Below are a couple of presentations from the Protein Aggregation and Stability session that I will summarize.
We’ve calculated our instantaneous clearance numbers for the benchtop studies that use sepcon chips. Even calculating per unit area, our chips are not clearing much volume in these experiments. I believe this is due to the very low flow rate (1 µL/min). Kayli is starting experiments to use higher flow rates with the same chips…
The company Protochips is making interesting microfluidic chips and systems for electron microscopy. See this page and this movie. Note their use of integrated spacers as thin as 150 nm to create a flow channel between back-to-back membrane chips. This not only relates to our work with Vincent in Ottawa, perhaps it gives us new…
I used COMSOL for finite element analysis (FEA) modeling of EOF and DEP at a microporous membrane in a PDMS microfluidic channel. Effects of two parameters were determined: Membrane thickness, and spacing between pores. The modeled membranes had a 25×25 um surface, and a thickness of either 100 nm or 500 nm. Pore diameter was…
Power and battery life for wearable hemodialysis. The pump(s) will consume the most energy of all the components of the system. Other power consumers could include, control circuits, wireless communication, display and warning lights, depending on design. A continuous display could consume a great deal of power if not handled correctly. LEDs and LCD indicators…
The relationship between the inlet and exit concentrations in a single pass over a membranes can be derived assuming first order loss to the membrane … (1) where is the local bulk concentration above the membrane and is the ‘elimination rate constant,’ a concept also used in drug delivery. this integrates across the membrane…
I have been talking with JP about getting some pnc-Si membranes coated with ~10-20 nm layers of Pd (or Pd-Ag) to do preliminary tests on hydrogen permeation devices. Tom and I are thinking of submitting a proposal. This kind of technology has been used industrially and follows the general principle shown below: These operate at…