Journal Club: Preview from Sabrina Leslie – CLiC with flow

Presentation in this post is based on the paper entitled “Large Area Synthesis of a Nanoporous Two-Dimensional Polymer at the Air/Water Interface”. Paper: Murray(King)JACS15 Supporting Information: Murray(King)JACS15 – SI Presentation Slides (PDF): Two-Dimensional Porous Membranes    

Introduction Currently, no FDA approved drug exist for the treatment of sepsis. Past sepsis pharmaceuticals attempted to target mediators of the innate immune response. These drugs, however, struggled to balance remedial immune suppression from complete immune knockdown in a patient population plagued my a maladative immune system. This fundamental issues is due in part to…

I did a quick experiment in order to show everyone what the Tecan allows us to do.  I made a dilution curve of rhodamine 6G in PBS and measured the absorbance and fluorescence with the fluorimeter. I first did an absorbance scan and found that the maximum absorbance was at 530nm (panel A).  Then I…

Experiments were conducted to determine how effectively protein is bound by suspended graphene oxide (GO) particles. This is important for our application because we hope to use GO as a membrane to bind toxins present in blood. BSA (bovine serum albumin) was used as the test protein. Test samples consisted of a mixture of BSA…

This week I set up some diffusion experiments with the inner membranes of wafers 187 and 310. From the TEM images posted previously, we see that these inner membranes have what appear to be either very small pores or small divots that do not pass entirely through the membrane. I allowed the protein standards to…

We want to create a structure that can more easily control the electric field inside of the Monolith cavities, by adding an electrode specific to each well. My solution is to create a hybrid film stack, replacing some of the SiO2 spacer with a gold layer that is in fluidic contact on the walls of…