Temp-controlled 'nanopores' may allow detailed blood analysis

Introduction I am working part time in collaboration with the Schwarz lab (CMSR, University or Rochester) on a bacterial migration project that includes the use of SimPore’s membranes. In order to increase throughput, Aline was contracted out to manufacture multiplex devices designed by Jim, Elysia Masters and myself. One aspect we would like to probe…

w565 is permeable to rhodamine. I tested two chips using 100uM rhodamine using a time step of .5 minutes. Click on pictures to see animations. position (1,-1) – While trying to do this first sample, MATLAB crashed and I was forced to take the movie about 7 minutes after the start. There is also a…

Last week, we created a series of wafers that were RTPed at four different temperatures between 900 C and 1000 C.  Below is a comparison of the 900 C (left) vs. 1000 C RTP (right) wafer. We see that a difference of 100 C shifts the cutoff ~10 nm.  The pores are also the roundest…

UPDATE: A look at long and short crystal dimensions (9/1/10): DLS vs. Crystal Sizes – Newest version 8/30/10 Here is a comparison of sieving curves using DLS or estimated crystal dimensions of proteins. DLS: 24 hours sieving curve. 48 hours sieving curve. Estimated longest crystal dimension: 24 hours sieving curve. 48 hours sieving curve.

I reran a set of hydraulic permeability tests at 16.56psi (3500RPM) hoping that this would clarify the previously collected data at the 21.63psi (4000RPM) and the 33.79psi (5000RPM) range that did not seem to agree with the trend of the other data points. As shown above this point still does not seem to be in…