Viscosity vs. [BSA]
Are you wondering why Dean has yet to go beyond 30% BSA in his clearance studies? Here is why …
Are you wondering why Dean has yet to go beyond 30% BSA in his clearance studies? Here is why …
Parylene-C is a biocompatible, inert, FDA-approved and nondegradable material, which can be used to fabricate mechanically robust thin membranes. Parylene is used in the medical device industry for coating implantable devices and in the microelectronics industry as insulator. Furthermore, it has been used in biomedical research for a wide variety of applications. In addition, parylene-C…
Hello Everyone, Kilean helped us to set a training session for NanoParticle Tracking Analysis (NTA) in UR Medical Center. For this training session, i had 4 samples including: Beads, Liposomes, Media + 10% serum, and PBS. Here is a summary of what we learned, i am also summarizing a paper that i found for comparing…
This post is a recap on the nanosphere lithography based membrane patterning process. The results shown here are from a non-optimized run of the process. The image below shows an overview of the fabrication process used. Below you can see optical micrographs of an etch test we performed on a TEOS sample with the…
On Monday I presented our progress on the hemodialysis project for the Coulter Foundation. They seemed very pleased with our progress and impressed with our team. Its a tough crowd and for the first time, I sensed they had confidence in us. I’ve uploaded my presentation to the blog (PDF; ppt). Their primary points of…
Earlier in the week I retested the 100K microcons in our wet-wet EQ format. When I last ran them this way I calculated very little flow and very small permeability values. I noted that there was a rather large air pocket collecting on the underside of the membrane in the plastic support structure; most likely…
Recently, several studies on Staphylococcus aureus (S. aureus) have been hindered due to poor performance from assays using the µSiM-Canalicular Array (CA). As discussed here, we attempted to improve assay performance by coating our membranes with fibronectin. This did not work well and instead left us in a state of confusion as we did not…