Our new diffusion chamber is finally here. Take a look at the photos first – in our next group meeting you can see the real thing. Today I will test its usability and reliability. Please keep in mind this is only the prototype, there must be upside space for improvement.
See Microfluidic Mold Making for instructions. I have assembled 3 more Barrett Chamber/ SC114 pnc-Si microfluidic devices this week. Currently, there are 2 Barrett chambers remaining and the mold is missing. The mask to make the mold still exists, however, there was a lack of N2 gas for processing (spin-coater requisite), so Henry and I…
As the title states, this post is about shifting an arbitrary pore distribution in an NPN layer. Why would we want to do this? We believe that the underlying pore distribution and shape influences the properties of many of our devices (my SERS sensor work included). Jim has coined the term ‘bowl-with-a-hole’ to describe the…
Here is a PDF of the presentation I plan to give at BMES this year. The presentation is first an overview of our SiO2 membranes for cell barrier and co-culture models and then a brief summary of our cell-substrate and cell-cell interactions on porous and soft substrates. I am currently working on getting it under…
The following contain updates from a group of Swiss collaborators working with NPN for a BBB mimetic. The movies are important because they demonstrate T-cell/endothelial interaction including transmigration and because they show how using vacuum pressure can rapidly cause vacuoles to grow in endothelial cells. BBB flow chamber PPT
Isabelle Linares_MPS World Summit 2024_Poster
Here is a slightly enhanced version of Mike’s latest hydraulic permeability data for commercial devices with PES membranes. The data at 22 and/or 34 PSI are a bit strange. Still the long-term trend seems downward. Similar data for PNC-Si membranes should show no pressure dependence. We need to get a version of this figure that…