Journal Club for June 26
Very last minute but here goes … Voting closes at 7 pm tonight. Vote for 2!
[yop_poll id=”4″]
Very last minute but here goes … Voting closes at 7 pm tonight. Vote for 2!
[yop_poll id=”4″]
A group published a paper in Lab on a Chip (2012) using track-etched membranes for electro-osmosis. There are a lot of eerily familiar terms and concepts in the paper. The title even sounds familiar: Low-voltage electroosmotic pumps fabricated from track-etched polymer membranes They created a device with metal mesh electrodes on the opposite sides of…
Note: a postscript regarding an assay to determine the activity of our MMP-2/MMP-9 inhibitor was added to this post on June 14, 2021. Introduction The blood-brain barrier (BBB) plays an important role in maintaining brain chemistry by restricting the permeability of small molecules and cells. Inflammatory diseases may disrupt the BBB and promote the development…
Following images show the diffusion profile of rhodamine across pncSi as observed in the timelapse movies. Looking at the profiles no significant difference is observed between the non RTPed and RTPed samples. Non RTP sample: RTP sample:
Here is the figure we talked about in the last meeting. For each specific membrane, I’ve plotted both the experimental permeability and the permeability calculated from the theory. You can see in some cases they are close, but in others they can be pretty far off. Omitted from this chart are retests. Updated: Graph is…
I attempted to clear the large format lift-off devices (from Josh). I was unable to clear, in a reasonable amount of time (< 2 hours) by pumping IPA. So I switched to PBS then Blood and blue-dyed PBS (dye is estimated to be between 10 nm and 500 nm, obviously the amount of dye near…
A third fibroblast (L1 3T3, P22) growth test was conducted using glass, untreated and tissue culture treated plastic, and RTPed pnc-Si (W509) as substrates. Cells were grown in DMEM +10% FBS changed every 48 hours. R values are for the fit N=No*exp^(r*t), where r has units of divisions/hour. For this trial fibroblasts grown on glass,…