New wafers permeabilty and burst pressures data

Here’s the latest news from the production front: We are still struggling with the pinhole issue. Last week, Chris and JP tried a matrix of conditions to try to eliminate the particle contamination. Efforts included using the CO2 snow cleaner and a piranha solution clean. After etching the first wafer which saw only the piranha…

We want to create a structure that can more easily control the electric field inside of the Monolith cavities, by adding an electrode specific to each well. My solution is to create a hybrid film stack, replacing some of the SiO2 spacer with a gold layer that is in fluidic contact on the walls of…

A couple weeks ago, I presented a potential figure for my paper that didn’t make sense.  So, I did a couple more controls and put together this new figure.  This is the “diffusion through ‘non-porous’ SC348/cut-off of nonporous membranes” figure.  I redid it to include SC348 (the nonporous sample) and ‘typical’ pnc-Si as % of…

I reran a set of hydraulic permeability tests at 16.56psi (3500RPM) hoping that this would clarify the previously collected data at the 21.63psi (4000RPM) and the 33.79psi (5000RPM) range that did not seem to agree with the trend of the other data points. As shown above this point still does not seem to be in…

One question we recently had was what does it look like when we perform a separation experiment when a membrane has a pinhole. I selected two membranes off 621 that appeared to have pinholes on both slits. I applied 1:2 standards to the top and allowed to diffuse for 24 hours. I collected the retentate…

Sugiura 2010 (Anal. Chem) This paper details a PDMS microfluidic system to perform dose response assays  (what I’m hoping to achieve over this summer). They use serial dilutions to get separate trials spanning six orders of magnitude, showing an optimal dosage to kill HeLa cells. Their system is very efficient, using very shallow channels and balancing the…