The future of the Goergen Hall Basement

In this post I address every objective we started with and summarize our results: a) Building of research capacity at Fisher. —–> We would like to to produce our lipid-based nano particles in a cheaper and more reproducible way. For the last 4 weeks Ryan has been producing phosphatidylcholine liposomes.  Depending on the rate of flow, we…

Previously, we showed that our method of pll-peg coating is effective for creating non-fouling substrate which can prevent protein adsorbtion, and this method can be used to create a non-fouling pattern on the surface. In the next step, we wanted to make sure that whether our peg coating is effective for preventing cell adhesion or…

This is probably not of general interest, but for the sake of full disclosure, I have spent considerable time working with our wafer supplier (Virginia Seiconductor) to resolve some issues regarding the surface quality of their wafers. It would have been much more productive to simply switch suppliers, but unfortunately, they are the only place…

Introduction EC Apicobasal polarity in immunity has and will continue to be a theme of my thesis. I have presented on bits and pieces of this work over the past year or so, but now that this work is under review and more or less complete pending reviewer comments, I wanted to summarize our finds…

In anticipation of the pnc-Si separation paper, I have performed a couple of preliminary separations using NanoSeps and MicroCons. I applied 200ul of 1:20 brain extract ( ~.9mg/mL) to 100k NanoSeps and MicroCons, and I spun the samples for 3 minutes at 14000g. I had wanted to collect the retentate as is from the top,…