We have the Tecan M200 until Oct. 6th!

Demos of the Molecular Devices M2e and Tecan Infinite M200 are done.
Erik from Tecan left us the M200 to use until October 6th.  Please come try out your assays on it.  Or check sensitivities.  Jess or I could probably steer you in the right direction as far as the software is concerned.


My impressions of Molecular Devices M2e:
1. The fluorescence reader wasn’t working on the brand new demo.
2. Cool Pathcheck feature that detects different volume levels in plates and automatically adjusts height of reader to correspond to standard 1cm pathlength. This can correct for sloppy pipetting.
3. Temps up to 40C, no control of mixing (either on/off).
4. Customizable plate setups.
5. Lots of pre-programmed assays in the software.
6. Ability to take many readings in the same well. Can “image” a well.
7. Totally Windows-based software. Linked into MS Word and MS Excel for Data Analysis. Easy to use. Probably not useful for analysis.
8. TRF and luminescence run off of fluorescence detector.
9. Two East Coast Apps personnel.
10. 9nm spectral bandwidth for fluorescence


My impressions of the Tecan Infinite M200:
1. Software called iControl and Magellen – seems better than Molecular Devices but still some inefficiencies (I think)
2. Can write customizable plate setups.
3. Has controllable shaking, either linear or orbital! Temps to 45C
4. Ability to take many readings in the same well. Can image a well – this looks better than MD.
5. Possibly useful data analysis in Magellen. Certainly more powerful than what we saw with the MD with some cool QC tricks.
6. Can do TRF.
7. No preprogrammed protocols. Can write own methods or just take quick raw data scans.
8. 5nm spectral bandwidth for UV wavelengths, 9nm otherwise.
9. Can only do ABS in cuvettes, but comes with special insert to do cuvette fluorescence in plate format.
10. No pathcheck! Erik showed us a method that calculates the pathlength though, so you can still get this information.
11. More East Coast Apps people.
12. Can add injectors or luminescence to this machine in the future.


Check out the Equipment -> Equipment Wish List -> Fluorimeters for more information on these instruments.

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