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Fisher Team update: Half way there
ByFernandoWe still have plenty of things to do, but after five weeks working at the UR, we have come a long way: – Chip production for instructional use: done – Design and production of SU8 mold: done – Protocols for (@Fisher) manufacture of micro and milli (silhouette) fluidic devices: done – Construction and testing of chips…
Nair, R. R., et al. (2012). “Unimpeded permeation of water through helium-leak-tight graphene-based membranes.” Science 335(6067): 442-444.
ByJimNair(Geim)Science12 Supplement Laminates of GO from 0.1 to 10 um thick on copper foil with an etched hole of 1 cm. Casually mentions >1.5 psi applied to materials < 1 um thick over 1 cm diameter hole. This seems to suggests a strong burst pressure but with no real data or experimental details, this is…
Aggregation of 20 nm NPs, IgG, and Tween 20
We had previously tested different surfactants to see if we could get 20 nm polystyrene beads and IgG to stay in suspension while filtering with the centrifuge. We found 0.1% Tween 20 to be sufficient when dealing with 10:1 (5×10^14) 20 nm NPs and 1mg/ml IgG. During the reverse centrifuge studies we mixed 10^15 particles/ml…
The Sieving Coefficient for Our Membranes is Time-Dependent (modeling post)
We’ve known for some time that the sieving coefficient of our membranes changes over time. The reason for this is that at the start of the separation the concentration just above the membrane is the same as the bulk concentration, but as more and more fluid begins to pass through the membrane we get concentration polarization, and the membrane…
Dialysis Rotation Project
Introduction Throughout my rotation, I have been working on the dialysis project with Alec. The goal was to set up a multi-pass system to analyze the membrane’s ability to separate different molecules in blood. The critical separation is between β2-microglobulin (12 kDa) and albumin (66 kDa) – β2-microglobulin is a large toxin that needs to…
Principles of Mold Making for Microfluidic Rapid Prototyping
See Microfluidic Mold Making for instructions. I have assembled 3 more Barrett Chamber/ SC114 pnc-Si microfluidic devices this week. Currently, there are 2 Barrett chambers remaining and the mold is missing. The mask to make the mold still exists, however, there was a lack of N2 gas for processing (spin-coater requisite), so Henry and I…
