No individual meetings today …

5nm BSA-Au appears to be 12.7nm.10nm BSA-Au is 18nm. Dilution dependent size change of 5nm BSA-Au. One theory for the size change was that residual BSA was combining with the Au peak and for some reason dilution of the BSA was causing a migration of the peak. This doesn’t necessarily make much sense as the…

From Jess’ manuscript … From Wikipedia … From Tom’s ACS nano paper … The Dagan equation (2) for flow through short pores used to predict flow through pnc-Si is given by: where r is the average pore radius, DP is the pressure drop across the membrane, l is the membrane thickness and m is the…

Hello Everyone, The goal of these experiments was to study the effect of exosomes on wound healing. We wanted to study, first importance of exosomes  for migration of FBs and eventually closure (healing) of the wound and second effect of exosomes derived from ADSCs on FBs migration. In order to test our hypothesis, we designed…

When we are trying to optimize the capture of exosomes in the tangential flow system, it is important to understand how particles are behaving in the flow. Initially, we tried to do this last summer by looking into the particle tracing package for COMSOL, but that required a complete overhaul of the software (a new…

The Tecan Nanoquant plate is amazing.  For those of you who are unaware, we were able to demo a quartz plate that enabled absorbance measurements with only 2ul drops.  It took a little bit for me to figure it out, but it really is a great tool for this kind of study. The ultra low…

The blue line reflects measurements taken with my zetapotential setup. Each data point is the average of three independent measurements of zetapotential (a new 3-slot SiN wafer 1024 chip for each measurement) and the linear fit for the pressure vs. streaming potential was at least R^2 > 0.92. Error bars come from the standard deviation…