EO at 1 mM vs 100 mM salts & the role of a meniscus in pressure measurements

In evaluating the usefulness of our membranes for cell culture, it is important to understand if and how cell growth is affected by the surface.  The desire is that they be consistent with standard culture substrates (i.e. Tissue Culture Plastic (TC)). I performed two growth trials using HUVECs (Human Umbilical Vein Endothelial Cells), one focusing…

Production this week focused on varying the RTP temperature of membranes deposited under identical conditions. wafer 316 – 800 C RTP (120 s) (0,-5) @ 50 kx Material still appears to be amorphous. Wrinkled at edges. wafer 318 – 900 C RTP (120 s) (0, 0) @ 50kx (-5, 0) @ 50kx A few, very…

With our virus sensor paper now published, my journey with virus diagnostics, at least for now, comes to an end. Keeping with the theme of modifying silicon surfaces for interaction with pathogens, I am now switching gears to developing models for bacterial infection. This is currently taking shape in an effort to coat our silicon…

In Episode 3 of this series, I have begun working towards improving my COMSOL modeling for particle capture. In addition to running simulations, I need to run experiments to try and correlate real world solutions with simulated results. One of the major focus points of my work has been trying to explain the shape of…

Introduction When concerning the issue of adherence on any substrate, the main two interactions that matter most are that of the cell interacting with the basement membrane (whether cell produced or artificially added) or the interaction between the protein based basement membrane and the substrate providing structure for cell culture; in our case SiO2 membranes….