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COMSOL model of SiMPore Liftoff device
I drew an approximation of the SiMPore liftoff device and ran the COMSOL model with 1 mL/min urea fluid flow in the upper channels and 2 mL/min dialysate in the bottom channels. With this initial model, the urea was cleared to 40% (60% removed). This is an instantaneous urea clearance rate of K= 0.6 mL/min….
Sepcon vs Cloning ring
I carried out this experiment in order to rule out any effect due to geometry of the setup in our discoloration experiments in Sepcon. I used a cloning ring and mimicked the Sepcon as shown in the figure below. The only difference is the o-ring which is absent in the cloning ring setup. To cover…
100K Microcon "duds"
ByMike HI few weeks ago I posted some flow rate data based on the 100K microcons in which three of the four membranes worked fine and the other appeared to be a “dud”. I pulled the four systems apart and used the digital calipers to measure the membrane thicknesses and found the following. – The three…
WordPress updates
I’ve upgraded the WordPress publisher to version 2.6. The most useful change is the ability to track changes to any post/page, compare revisions, and revert to an older version. Here’s a video showing the changes: https://videopress.com/v/mARhRBcT/fmt_std Additionally, I’ve installed some plug-ins that should make posting and keeping up with new posts easier: There is now…
Rhodamine and Fluoroscein Diffuse through SC269
ByMike HYesterday I posted my results from a BSA diffusion experiment using “treated” and “untreated” SC269 samples. To ensure that the pores in SC269 are indeed open I took a step backwards and set up a diffusion experiment using small dye molecues; rhodamine and fluoroscein. Using Jess’ diffusion cell I set up a matrix to test…
Protein Adsorption on silanized NPN Chip
ByHenryWe are working with the Shestopalov group to silanize the nanoporous silicon nitride (NPN) membrane chip. In an ideal scenario, the silane would then be conjugated to PEG to ward off protein adsorption. In the presented work, we study protein adsorption on both the untreated and the silanized NPN chips using epifluorescence as the imaging modality….