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Sepcon-Transwell hybrid devices
I’ve been working with the Corning transwell inserts and our SepCon units a bit recently. The addition of the Dremel last week has allowed better control while cutting the transwells, even without the right angle attachment (which will allow cutting in the “drill press” mode). I attached a picture of the process and final unit….
Quick Nanoparticle Separation Update
20nm polystrene beads in 1x PBS passed through w218. This wafer looks a little strange, like it was not fully etched (Dave do you know what happened to this one?). This was just a first stab at the benchtop diffusion with PS, so I didn’t use a “good” membrane. At any rate, the PS went…
Status the 'Harold Smith' Project
ByJimThis is my attempt to summarize where we are with our investigation into the use of membrane arrays in high throughput screening. The effort is known colloquially as the ‘Harold Smith Project’ because the model protein system comes from Harold and is inspired by work in his laboratory on HIV. The principle being tested is…
STED Imaging of Silica Beads
ByKileanTo try to calibrate the STED for imaging on our membranes, Bill and I have been trying to use 50 nm silica beads that have been captured on the membrane. However, we discovered initially that the beads were actually not too easy to work with and clumped like crazy. On STED, we weren’t really able…
2017 Spring Meeting – Materials Research Society
Hello everyone, this post is a summary/recap of the MRS Spring meeting that was held in Phoenix, Arizona this past week (April 17 – 21). Here is an overview of two sessions: Molecular and colloidal plasmonics – Synthesis and applications (ED14) Jennifer S. Shumaker-Parry, Associate Professor at University of Utah (http://shumaker.chem.utah.edu/) Combined top-down/bottom-up for the fabrication…
ECMO: Results and Conclusions
After several months of modeling, experimenting, thinking and rethinking, it’s finally time to talk about the conclusions we can draw about nanomembrane ECMO. These conclusions take into account only blood oxygenation, and not blood decarboxylation, which is a different therapy that I have not modeled. You can find my description of the model here, and…