In light of technical difficulties associated with the current liftoff device design, I’ve been working on a slight alteration to the design with an eye towards reducing leaking and improving the shape of the flow in the dialysate chamber. The shape of the blood conduit has been demonstrated to be successful in distributing the flow fairly…
LabChip_20160430
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While experimental results are still forthcoming, I thought I’d make a post about the nature of the model I’ve constructed for ECMO. This model is the one that my experiments are seeking to validate; so to be clear, this model is founded entirely in theory for now. ECMO shares some obvious similarities with hemodialysis — blood…
I attempted to clear the large format lift-off devices (from Josh). I was unable to clear, in a reasonable amount of time (< 2 hours) by pumping IPA. So I switched to PBS then Blood and blue-dyed PBS (dye is estimated to be between 10 nm and 500 nm, obviously the amount of dye near…
From my last blog post, was talked about designing an assay whereby the NPN filter would exclude DNA-conjugated gold nanoparticles while allowing short DNA to pass. Since then, I (with the help of my colleague Dan Tassier) have been wrestling with gold nanoparticles to find conditions in which the nanoparticles were stable, while also allowing…
As I’m approaching the end of my time here at UofR, there’s one last thing I’d like to fit into my thesis: experimental validation of the ECMO model. In this post I’m going to describe the experimental design, and in a future post I’ll discuss the model in more detail (pending a more complete set…
It has been a constant theme in our EO efforts as well as our energy harvesting efforts that our electrodes need to be as close as possible to the surface to see an effect. In Jess’s early EO work, we found that our chips could be used as EO pumps that were vastly more thermodynamically…
I don’t think I ever posted it on the blog, but two years ago I discovered something neat. At the time, I was trying to make my nanofluidic transistor, and I was reading Marina’s thesis. She tried to improve the efficiency of our EO pumps by putting silver films directly on the front and back…
Two years ago (blog post), I asked Professor McAleavey to help me see if we could use NPN chips to generate ultrasound. I’d found a paper (An exact solution of AC electro-kinetic-driven flow in a circular micro-channel) that suggested, given the geometry of our chips, that if the chips could be used to generate sound, they’d…