From SiMPore’s Basecamp thread … These are the nanopore characteristics. So between 14% and 20% porosity across the wafer and between 43 nm and 50 nm average pore size. So a little under-sized. I hope T-Cells and Monocytes can get through! 0.625% microporosity 0.625% microporosity
Wright, E., Miller, J.J, Csorda, M.. Gosselin, A.R., Carter, J.A., McGrath, J.L., Latulippe, D.R., Roussie, J.A. (2020) Development of Isoporous Microslit Silicon Nitride Membranes for Sterile Filtration Applications Biotechnology & Bioengineering https://doi.org/10.1002/bit.27240 DesOrmeaux, J. P., Winans, J. D., Wayson, S. E., Gaborski, T. R. , Khire, T. S., Striemer, C. C., and McGrath, J. L….
Design and Manufacturing Plans from Aline: 2019-09-23 Rochester Assembly Step by Step Prototype Runs @ ALine Post-fabrication assembly (cutting with lower power to eliminate bubbles) …
Because of the non-linear dependence of volumetric flow rate on pore size … where t is the membrane thickness and r is the pore radius, large pores contribute disproportionately to the total flow through a membrane than small pores. The magnitude of this phenomenon can be appreciated by using the Dagan equation to calculate the…
We have been collaborating with Britta Engelhardt’s group at the University of Bern in Switzerland since Tejas and I met them at the CNS Barriers conference in Paris in 2015. They are interested in studying live T-cell transmigration across human BBB models as part of their research program in Multiple Sclerosis (MS). Prior to working…
[latexpage] The solution to the problem of diffusion from a semi-infinite solution to a perfectly absorbing surface is found on page 32 of Crank’s classic text (The Mathematics of Diffusion): \begin{equation} \frac{C(y,t)}{C_o} = erf(\frac{y}{2\sqrt{Dt}}) \end{equation} Where D is the diffusion coefficient is the initial concentration everywhere in the bulk and erf is the error function….
[latexpage] This will be at least a three part series. Here in Part I, we will establish why adding flow to electrophoretic sensor (ssNP) is a bad idea. In Part II we will show why microfluidics is a benefit to adhesion-based sensors. In Part III we will explore the ability of a NPN/ssNP dual membrane…
1-5-2018 Final tRNA Presentation – By Jon Flax (Beckham Group) Modulated Expression of Specific tRNAs Drives Gene Expression and Cancer Progression
We have been in discussions with a large membrane company (lets call them Big Filter Inc.) on the topic of using our membrane for virus applications. Josh Miller did a rather remarkable thing and affixed 5.4 mm NPN chips into their standard housings so they could test them directly. Using these devices BF Inc. tested…
Grand Ballroom A Chair: Baoxia Mi & Zhiping Lai 09:00-09:25 [O8.01] Synthesis of graphene oxide membranes and their behavior in water and isopropanol A. Aher*1, Y. Cai1, M. Majumder2, D. Bhattacharyya1 1University of Kentucky, USA, 2Monash University, Austria 09:25-09:50 [O8.02] Carbon nanotube hollow fiber membranes R. McGinnis*1, K. Reimund2, B. Freeman2, L. Xia3, J. McCutcheon3 1Angstrom…