Summary I want to imitate the material properties from 1085 as they have given us the best SERS performance to date. We have the best information that we’ve ever had before imitating the nanostructure and nanotopology from the MgF2. Our belief is that getting infilled Au close together in a nanopore dramatically enhances the electric…

Hello Everyone, As you probably remember, We have been working on optimizing Track Etched membranes devices since last semester, these membranes are 80 nm pore size and our beads are 100 nm in. We have been working on the design to make devices work since the first day of these experiments because of different reasons like…

This post is a recap on the nanosphere lithography based membrane patterning process. The results shown here are from a non-optimized run of the process. The image below shows an overview of the fabrication process used.   Below you can see optical micrographs of an etch test we performed on a TEOS sample with the…

In previous experiments attempting to culture ADSC on non-porous and porous (0.5 µm, 3.0 µm) SiO2 membranes, we were having difficulty getting the ADSC to attach to the membranes. A majority of the ADSC did not appear well-spread. While in culture or staining, ADSC would detach from the membrane with little to no agitation. Changes…

Hi all, Recently we finished drafting the manuscript titled “Porous substrates promote early endothelial migration at the expense of fibronectin fibrillogenesis.” This manuscript will feature the cover illustrated by Brad (our new medical illustrator in the Gaborski Lab):   Long story short (another illustration by Brad): Left (nonporous control substrate): cell traveled slower, covered smaller…

We are happy to be back this summer. Anthony has been working on setting up a system that mimics Kilean’s dialysis devices. Our approach is different in two important ways. First, we are using PETLs, instead of PDMS/glass.  For those who are not familiar with PETLs, here is a short summary: Commercial laminating pouches made…

Some background and a quick summation since I have done a great job at avoiding posting. My undergrad background before the lab Chemistry, physics, math (minor) and a random psychology minor biology I questionably knew what a cell was Overarching theme Putting a microarray on top of the membranes for cell culturing Currently cells are…

When we are trying to optimize the capture of exosomes in the tangential flow system, it is important to understand how particles are behaving in the flow. Initially, we tried to do this last summer by looking into the particle tracing package for COMSOL, but that required a complete overhaul of the software (a new…

Wafer 1148 was produced roughly around the same time that the wafer I used to make my oldest MgF2 material (wafer 1085) was produced. We know that some of the NPN material from that time was not etched all the way through, creating pores that look like a ‘bowl-with-hole’. I believe the shape of the…